Pursuing breakthroughs in the study of mitochondria

 Dr. Rosemary Stuart researches the complex inner workings of mitochondria. Cells require ATP to power their workload, -and in unlocking energy from it, they convert ATP into a form of cellular spent fuel known as ADP. That's where a network of five enzymes in the mitochondria kicks in. Through a process called oxidative phosphorylation, this enzyme system (known as OXPHOS machinery) pulls in ADP from the cell and converts it back into ATP, fresh fuel to keep the cell running.

 Stuart’s team, up until a few years ago, focused primarily on one important mechanism – how much OSPHOS machinery gets built in the first place. This investigation remains a fruitful project in Stuart’s lab, funded by a three-year $540,000 grant from the NSF.

 Then a few years ago, team members, including Andrew Furness, Arts ’07, discovered a previously unknown mitochondrial protein. Hig1 physically joins two of the five complexes in the OXPHOS system and appears to help them coordinate their activity. Through a $340,000 grant from the National Institutes of Health, researchers in Stuart’s lab are working to elucidate this interaction. Read more

 

 

NEWS AND EVENTS

Dr. Bassler to present Smith Lecture April 4, 2014 at 3:00PM

Spring Seminar Series Announcedpdf

 

Dr. Pinfen Yang promoted to full professor

 

Read our Fall 2013 eNewsletter

Megan Mohnen receives V. Duane Rath Merit Scholarship

2013 Graduate Student Awards

Undergraduate Awards presented to Laura Mark, Joseph Burclaff, Sihui Yang and Melissa Budelier

Dr. Allison Abbott promoted to associate professor

Wisconsin Native Tree Collection Brochure Updated

Dr. Lisa Petrella joins Biological Sciences Faculty

 

 

 

 

 

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